Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival

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Caspase 3 in breast cancer.

PURPOSE An inability to undergo apoptosis is widely thought to contribute to both tumorigenesis and tumor progression. One of the key mediators of apoptosis is the thiol protease caspase 3. In this investigation, caspase 3 mRNA and protein expression in breast cancer was examined. EXPERIMENTAL DESIGN Caspase 3 was measured at the mRNA level using reverse transcription-PCR and at the protein l...

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ژورنال

عنوان ژورنال: Apoptosis

سال: 2016

ISSN: 1360-8185,1573-675X

DOI: 10.1007/s10495-016-1323-5